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Tranexamic Acid(1197-18-8)–Kiʻi Hōʻike ʻia API kanaka
  • Tranexamic Acid(1197-18-8)–API kanaka

Tranexamic Acid(1197-18-8)


Helu CAS: 1197-18-8

EINECS Helu: 356.2222

MF: C8H15NO2

Hōʻike huahana

Wehewehe Hou

Hōʻike huahana

● Tranexamic Acid(1197-18-8)

● CAS No.:·1197-18-8

● EINECS Helu: 356.2222

● MF: C8H15NO2

● Pūʻolo: 25Kg / Drum

● ʻO Tranexamic acid (TXA) he lāʻau lapaʻau i hoʻohana ʻia no ka mālama ʻana a i ʻole ka pale ʻana i ke kahe nui ʻana o ke koko mai ka ʻeha nui, ke kahe ʻana o ka hānau ʻana, ka ʻoki ʻana, ka wehe ʻana i nā niho, nā koko ihu, a me ka haʻi haʻahaʻa.[2][3]Hoʻohana ʻia no ka angioedema hoʻoilina.[2][4]Lawe ʻia ma ka waha a i ʻole ma ke ʻano o ka vein.

Mechanism o ka hana

ʻO ka waika Tranexamic kahi analog synthetic o ka amino acid lysine.Hoʻohana ia ma ke ʻano he antifibrinolytic ma o ka hoʻopaʻa ʻana i ʻehā a ʻelima mau wahi lysine receptor ma plasminogen.Hoʻemi kēia i ka hoʻololi ʻana o ka plasminogen i plasmin, e pale ana i ka hoʻohaʻahaʻa ʻana i ka fibrin a me ka mālama ʻana i ke ʻano o ke ʻano matrix o fibrin. ʻO ka waika Tranexamic ma kahi o ʻewalu mau manawa o ka hana antifibrinolytic o kahi analogue kahiko, ε-aminocaproic acid. ka hana o ka plasmin me ka ikaika nawaliwali (IC50 = 87 mM), a hiki ke ālai i ka pae hana o ka urokinase plasminogen activator (uPA) me ka kiko'ī kiʻekiʻe (Ki = 2 mM), kekahi o nā mea kiʻekiʻe loa ma waena o nā serine proteases.

Nā hana o ka waikawa Tranexamic

Hoʻohana pinepine ʻia ka waika Tranexamic ma hope o ka ʻeha nui.[13]Hoʻohana ʻia ʻo Tranexamic acid e pale a mālama i ke kahe o ke koko ma nā ʻano ʻano like ʻole, e like me nā kaʻina hana niho, ke koko menstrual kaumaha, a me nā ʻokiʻoki me ka nui o ke kahe koko.

Nā mea ho'āʻo Koina Pharmacopeial Ka hopena hoao
NA HUA ʻAno: Keʻokeʻo a ʻaneʻane keʻokeʻo paha, ka pauka crystalline ʻO ka pauka kristal keʻokeʻo
Hiki ke hoʻoheheʻe ʻia: Hiki ke hoʻoheheʻe ʻia i ka wai a me ka waikawa acetic glacial, hiki ʻole ke hoʻoheheʻe ʻia i ka acetone a me ka ethanol (96%) Holo
IKE Infrared Absorption Spectrophotometry: IR spectrum i kulike me Tranexamic acid CRS Holo
HOAO pH (2,2.3) 7.0 〜8.0 7.4
Nā mea pili (HPLC2.2.29) haumia A≤ 0.1 % ʻAʻole ʻike ʻia
haumia B≤ 0.2% 0.03%
Nā mea haumiaC

Nā mea haumia ʻole≤ 0.10% Nā mea haumia D

Nā mea haumia ʻē aʻe

0.002%

0.001%

ʻAʻole ʻike ʻia

Huina o na haumia i hoakaka ole ia≤ 0.2% 0.003%
Hōʻike ʻia nā Halides ma ke ʻano he Klorida ≤140ppm <140ppm
Nalo ma ka maloo ≤0.5% 0.026%
Lehu Sulphated ≤0.1% 0.027%
HANA Pono i loko (Ma muli o ka maloʻo) 99.0% 〜101.0% 100.1%

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