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Gliclazide(21187-98-4)–Kiʻi Hōʻike ʻia API kanaka
  • Gliclazide(21187-98-4)–API kanaka

Gliclazide(21187-98-4)


Ka helu CAS: 21187-98-4

EINECS Helu: 323.4105

MF: C15H21N3O3S

Hōʻike huahana

Wehewehe Hou

Papa inoa Huahana

ʻO Gliclazide kahi lāʻau antidiabetic waha sulfonylurea.He keʻokeʻo keʻokeʻo a i ʻole ka pauka crystalline, ʻaʻole ʻono a ʻono ʻole.

ʻO Gliclazide kahi lāʻau hypoglycemic oral sulfonylurea oral me ka hana ikaika.Ua like kona ʻano me ka toluenosulfonylurea, ʻo ia hoʻi, ke koho nei ia i nā pancreatic β-cells e hoʻoikaika i ka huna ʻana o ka insulin a hoʻonui i ka hoʻokuʻu ʻana o ka insulin ma hope o ka ʻai ʻana i ka glucose, ʻaʻole hiki ke hoʻomaikaʻi wale i ka metabolism o nā maʻi maʻi maʻi, akā hoʻomaikaʻi a hoʻopaneʻe paha i ka hanana ʻo nā pilikia vascular diabetic.

Hoʻohana nui ʻia ʻo Gliclazide no ka maʻi maʻi mellitus type II me ka maʻi maʻi me ka hoʻomaka ʻana o nā pākeke kahi i kūpono ʻole ai ka ʻai a me ka hoʻomaʻamaʻa hoʻomaʻamaʻa ʻana a me ka ʻole o ka ketosis, a hoʻomaikaʻi hoʻi i nā ʻeha fundus a me nā maʻi metabolic a me nā vascular dysfunctions i nā maʻi maʻi maʻi.

Palapala noi

Hoʻohana ʻia ʻo Gliclazide no ka mālama ʻana i ka hyperglycemia i ka gliclazide-responsive diabetes mellitus o ka paʻa, maʻalahi, non-ketosis prone, type 2 diabetes.Hoʻohana ʻia ia i ka wā ʻaʻole hiki ke hoʻomalu ʻia ka maʻi diabetes e ka hoʻokele pono ʻana i ka meaʻai a me ka hoʻomaʻamaʻa ʻana a i ka wā ʻaʻole kūpono ka lāʻau insulin.

Hoao Nā kikoʻī Nā hopena o ka nānā ʻana
Ka nana aku Pauda keʻokeʻo a aneane keʻokeʻo. Pauda keʻokeʻo
Ka hikiwawe ʻAʻole hiki ke hoʻoheheʻe ʻia i ka wai;hiki ke hoʻoheheʻe ʻia i ka methylene chloride;hiki ke hoʻoheheʻe ʻia i ka acetone;hiki ke hoʻoheheʻe iki ʻia i ka ethanol (96 pākēneka). Kū i nā koi
ʻIkepili Kūlike ka spectrum absorption infrared me ka mea i loaʻa me ka Gliclazide CRS. Kū i nā koi
haumia B (Na HPLC) ≤2ppm 0.5ppm
Nā metala kaumaha ≤10ppm <10ppm
Nā mea pili (Na HPLC) haumia F ≤0.1% ʻIke ʻole ʻia
ʻO kēlā me kēia haumia ʻole i hōʻike ʻia ≤0.10% 0.04%
ʻO ka huina o nā haumia ʻē aʻe ma mua o F ≤0.2% 0.11%
Pohō ma ka maloʻo ≤0.25% 0.11%
Lehu hū ≤0.1% 0.03%
Nā mea hoʻoheheʻe koena (Na GC) Ethyl acetate NMT 2500 ppm 265ppm
N,N-Dimethylformamide NMT 880 ppm ʻIke ʻole ʻia
Hoʻāʻo 99.0-101.0%, ma ke kumu maloʻo. 100.0%
Ka hopena Kūlike nā hopena hōʻike me EP8.

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